Interpreting Efficacy Results from Cardiovascular Outcomes Trials


Interpreting Efficacy Results from Cardiovascular Outcomes Trials

The faculty for this program (short course) is Kevin C. Maki, PhD, Chief Scientist for Midwest Biomedical Research’s Center for Metabolic and Cardiovascular Health.  Dr. Maki specializes in the design and conduct of clinical studies in human nutrition, metabolism, and chronic disease risk factor management.  He holds Adjunct Faculty positions teaching Epidemiology and Biostatistics at the Illinois Institute of Technology and DePaul University, and has participated in more than 250 clinical trials and observational studies as an investigator, consultant, or statistician.

About the Course

Cardiovascular outcomes trials are integral to evidence-based cardiovascular medicine, and they are the most effective means for demonstrating that an intervention reduces major adverse cardiovascular events.  A sound understanding of the fundamentals of clinical study design and statistical methodology is essential for the interpretation of efficacy results from cardiovascular outcomes trials.  This webinar aims to deliver information for non-statistician research and health professionals about how to systematically evaluate and interpret results from cardiovascular outcomes trials.  The course will provide a review of the following concepts:

  • Comparing measures of cardiovascular event incidence between groups
    1. Relative risk
    2. Hazard ratio
    3. Odds ratio
  • Comparing event rates and treatment effects
    1. Relative risk reduction
    2. Absolute risk reduction
    3. Number needed to treat (or harm)
  • Pitfalls in making comparisons between cardiovascular outcomes trials, including the three key questions
    1. Who was treated (risk profile)?
    2. What outcomes were assessed?
    3. Over how long a period?
  • Additional factors to consider in the interpretation of findings from cardiovascular outcomes trials
    1. Evaluating the roles of chance, bias and confounding
    2. Factors affecting validity and generalizability
    3. Assessing the potential for type I and type II statistical errors

Who will benefit from this short course?

This course aims to provide research and health professionals with important information to aid in their interpretation of results from cardiovascular outcomes trials.  Persons working or studying in the following fields will benefit from this program:

  • Primary Care Physicians
  • Subspecialists (Cardiology, Endocrinology, etc.)
  • Nurse Practitioners
  • Physician Assistants
  • Clinical Research Professionals

What will you receive?

With your purchase of Interpreting Efficacy Results from Cardiovascular Outcomes Trials, or any of the short courses sold by MB Clinical Academy, you receive:

  • A PDF of the course slides
  • Narrated audio/video recordings of the presentations (mp4 files)

How much does it cost?

The cost of this program is normally $39.  For a limited time, we will be offering at an introductory price of $29.


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