Our Blog

 

Bempedoic acid in conjunction with statin therapy for dyslipidemia management

By Aly Becraft MS and Kevin C Maki PhD | Apr 15, 2019 | 0 Comments

Bempedoic acid in conjunction with statin therapy for dyslipidemia management By Aly Becraft, MS; Kevin C. Maki, PhD Use of statins to reduce risk of cardiovascular disease is an effective treatment strategy,1 but the statin doses required to adequately reduce low density lipoprotein cholesterol (LDL-C) and non-high-density-lipoprotein cholesterol (non-HDL-C) levels and achieve optimal cardiovascular disease

Read More

The Effects of Icosapent Ethyl on Total Ischemic Events: An Analysis from REDUCE-IT

By Aly Becraft MS and Kevin C Maki PhD | Mar 26, 2019 | 0 Comments

The Effects of Icosapent Ethyl on Total Ischemic Events: An Analysis from REDUCE-IT By Aly Becraft, MS and Kevin C Maki, PhD   Statin therapy is highly effective for lowering low-density lipoprotein cholesterol (LDL-C), but many patients remain at risk for ischemic events, despite statin therapy.1 Elevated levels of triglycerides (TG) and TG-rich lipoproteins are

Read More

C-Reactive Protein Levels and Cardiovascular Events after Acute Coronary Syndrome: Results from a Secondary Analysis of the VISTA-16 Trial

By Aly Becraft MS and Kevin C Maki PhD | Mar 21, 2019 | 0 Comments

C-Reactive Protein Levels and Cardiovascular Events after Acute Coronary Syndrome: Results from a Secondary Analysis of the VISTA-16 Trial By Aly Becraft, MS; Kevin C Maki, PhD   Each year approximately 29% of heart attack (myocardial infarction) events in the USA occur in people who have previously had a heart attack.1 Even with ideal medical

Read More

Potential Role of Nut Consumption for Improving Insulin Sensitivity : Results from a Systematic Review and Meta-analysis of Randomized Controlled Trials

By Heather Nelson Cortes PhD and Kevin C Maki PhD | Mar 21, 2019 | 0 Comments

Potential Role of Nut Consumption for Improving Insulin Sensitivity : Results from a Systematic Review and Meta-analysis of Randomized Controlled Trials By Heather Nelson Cortes, PhD and Kevin C Maki, PhD   Worldwide incidence and prevalence of type 2 diabetes mellitus (T2D) diabetes are increasing at alarming rates, largely following increases in incidence of overweight

Read More

No Additional Benefits on Cardiometabolic Risk Parameters of Reduced Red Meat or Increased Fiber Intake in an Energy-restricted Diet

By Heather Nelson Cortes PhD and Kevin C Maki PhD | Mar 21, 2019 | 0 Comments

No Additional Benefits on Cardiometabolic Risk Parameters of Reduced Red Meat or Increased Fiber Intake in an Energy-restricted Diet By Heather Nelson Cortes, PhD and Kevin C Maki, PhD   To date, results from epidemiological studies have suggested that a high intake of red meat is associated with a higher risk of developing type 2

Read More

New Trial Suggests Light Therapy may be a Promising Intervention for Treatment of Depression with Type 2 Diabetes

By Aly Becraft MS and Kevin C Maki PhD | Mar 8, 2019 | 0 Comments

New Trial Suggests Light Therapy may be a Promising Intervention for Treatment of Depression with Type 2 Diabetes By Aly Becraft, MS; Kevin C Maki, PhD One in 11 adults have diabetes worldwide,1 with an estimated 25% of people with diabetes also suffering from depression.2 Co-occurrence of these diseases has been shown to increase risk

Read More

Suboptimal Triglyceride Levels Among Statin Users in the National Health and Nutrition Examination Survey

By Heather Nelson Cortes PhD and Kevin C Maki PhD | Feb 25, 2019 | 0 Comments

Suboptimal Triglyceride Levels Among Statin Users in the National Health and Nutrition Examination Survey By Heather Nelson Cortes, PhD and Kevin C Maki, PhD   Statin therapy is the primary treatment for dyslipidemia, even in those with moderately elevated triglycerides (TG).1  Hypertriglyceridemia, an independent risk factor of coronary heart disease (CHD), is defined as fasting

Read More

Association of Statin Adherence with Mortality in Patients with Atherosclerotic Cardiovascular Disease

By Heather Nelson Cortes PhD and Kevin C Maki PhD | Feb 24, 2019 | 0 Comments

Association of Statin Adherence with Mortality in Patients with Atherosclerotic Cardiovascular Disease By Heather Nelson Cortes, PhD and Kevin C Maki, PhD   There is little doubt of the role that statins play in the reduction of mortality risk, mainly attributable to a benefit on death from cardiovascular causes.  A meta-analysis of statin clinical trials

Read More

More Evidence that Low-density Lipoprotein Cholesterol and Triglyceride-lowering Genetic Variants Reduce Risk of Coronary Heart Disease

By Kevin C Maki PhD and Mary R Dicklin PhD | Feb 10, 2019 | 0 Comments

More Evidence that Low-density Lipoprotein Cholesterol and Triglyceride-lowering Genetic Variants Reduce Risk of Coronary Heart Disease By Kevin C Maki, PhD and Mary R Dicklin, PhD   The total cholesterol concentration in circulation is comprised of cholesterol carried by three main types of lipoproteins:  low-density lipoproteins (LDL), very-low-density lipoproteins (VLDL) and high-density lipoproteins (HDL).  VLDL

Read More

Viscous Fiber Supplements in Diabetes Control: Results from a Systematic Review and Meta-analysis of Randomized Controlled Trials

By Heather Nelson Cortes PhD and Kevin C Maki PhD | Feb 9, 2019 | 0 Comments

Viscous Fiber Supplements in Diabetes Control: Results from a Systematic Review and Meta-analysis of Randomized Controlled Trials By Heather Nelson Cortes, PhD and Kevin C Maki, PhD According to the recent 2019 American Diabetes Association (ADA) Standards of Medical Care in Diabetes, people with diabetes should increase their intake of viscous fiber from sources such

Read More