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A Review of Three Recently Published Papers on Dietary Approaches to Weight Loss and Fat Mobilization

By Kristen N Smith PhD RDN Mary R Dicklin PhD Kevin Maki PhD | May 24, 2018 | 0 Comments

A Review of Three Recently Published Papers on Dietary Approaches to Weight Loss and Fat Mobilization By Kristen N Smith, PhD, RD; Mary R Dicklin, PhD; Kevin C Maki, PhD, CLS   Background: There have been multiple papers published this year focusing on various dietary approaches for producing weight loss and their effects on weight-related…

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Participants with Elevated Lp (a) Had Greater than Average Benefit from Evolocumab in FOURIER

By Kevin Maki PhD | May 17, 2018 | 0 Comments

Participants with Elevated Lp (a) Had Greater than Average Benefit from Evolocumab in FOURIER Kevin C Maki, PhD, CLS, FNLA and Mary R Dicklin, PhD It has been known for decades that an elevated level of lipoprotein (a) or Lp (a) is associated with increased cardiovascular disease (CVD) risk.  The Lp (a) particle consists of…

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Differential Effects of n-3 and n-6 Fatty Acids on Carotid Plaque and Its Progression: Analyses from The Multi-Ethnic Study of Atherosclerosis

By Kristen N Smith PhD RDN Mary R Dicklin PhD Kevin Maki PhD | Apr 1, 2018 | 0 Comments

Differential Effects of n-3 and n-6 Fatty Acids on Carotid Plaque and Its Progression: Analyses from The Multi-Ethnic Study of Atherosclerosis By Kristen N Smith, PhD, RD, LD; Mary R Dicklin, PhD; Kevin C Maki, PhD, CLS, FNLA  Background: The process of atherosclerotic development is multifactorial involving inflammation, endothelial activation, oxidative stress and lipid accumulation…

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ODYSSEY Outcomes Trial: Topline Results and Clinical Implications

By Kevin Maki PhD | Mar 26, 2018 | 0 Comments

ODYSSEY Outcomes Trial: Topline Results and Clinical Implications By Kevin C Maki, PhD, CLS, FNLA; Kristen N Smith, PhD, RD, LD; Mary R Dicklin, PhD  Background: Cardiovascular disease (CVD) event risk is high in those with recent acute coronary syndromes (ACS), despite treatment with evidence-based preventive therapies. Prior research has shown that CVD event risk…

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24-Hour Urinary Collection Data Support Strong Associations between Sodium and Potassium Excretion and Blood Pressure in the National Health and Nutrition Examination Survey

By Kristen N Smith PhD RDN Mary R Dicklin PhD Kevin Maki PhD | Mar 5, 2018 | 0 Comments

24-Hour Urinary Collection Data Support Strong Associations between Sodium and Potassium Excretion and Blood Pressure in the National Health and Nutrition Examination Survey By Kristen N Smith, PhD, RD, LD; Mary R Dicklin, PhD; Kevin C Maki, PhD  Background: It is well established that hypertension is an important modifiable risk factor for cardiovascular disease (CVD),…

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Summary of Results from a Trial of a Novel Selective PPARɑ Modulator, Pemafibrate, on Lipid and Glucose Metabolism in Patients with Type 2 Diabetes and Hypertriglyceridemia1

By Kristen N Smith PhD RDN Mary R Dicklin PhD Kevin Maki PhD | Mar 5, 2018 | 0 Comments

Summary of Results from a Trial of a Novel Selective PPARɑ Modulator, Pemafibrate, on Lipid and Glucose Metabolism in Patients with Type 2 Diabetes and Hypertriglyceridemia By Kristen N Smith, PhD, RD, LD; Mary R Dicklin, PhD; Kevin C Maki, PhD  Background: Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of death in persons with…

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Substituting a Type-4 Resistant Starch for Available Carbohydrate Reduces Postprandial Glucose, Insulin and Hunger: An Acute, Randomized, Double-Blind, Controlled Study

By Kristen N Smith PhD RDN Mary R Dicklin PhD Kevin Maki PhD | Feb 15, 2018 | 0 Comments

Substituting a Type-4 Resistant Starch for Available Carbohydrate Reduces Postprandial Glucose, Insulin and Hunger:  An Acute, Randomized, Double-Blind, Controlled Study1  By Kristen N Smith, PhD, RD, LD; Mary R Dicklin, PhD; Kevin C Maki, PhD  Background: Dietary fiber (including a wide variety of nondigestible carbohydrates) is a noted shortfall nutrient in Western diets, despite the…

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An Independent Summary of Low-Density Lipoprotein Cholesterol Lowering With Evolocumab and Outcomes in Patients with Peripheral Artery Disease: Insights from the FOURIER Trial

By Kristen N Smith PhD RD LD Kevin C Maki PhD | Jan 12, 2018 | 0 Comments

An Independent Summary of Low-Density Lipoprotein Cholesterol Lowering With Evolocumab and Outcomes in Patients with Peripheral Artery Disease: Insights from the FOURIER Trial (Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects with Elevated Risk).1 An Independent Summary of Low-Density Lipoprotein Cholesterol Lowering With Evolocumab and Outcomes in Patients with Peripheral Artery Disease: Insights from…

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Breakfast Skippers Beware: Newly Published Data on Breakfast Patterns Identifies Association with Atherosclerosis, Independent of Cardiovascular Disease Risk Factors

By Kristen N Smith PhD RDN Mary R Dicklin PhD Kevin Maki PhD | Dec 19, 2017 | 0 Comments

Breakfast Skippers Beware: Newly Published Data on Breakfast Patterns Identifies Association with Atherosclerosis, Independent of Cardiovascular Disease Risk Factors Insights from the Progression of Early Subclinical Atherosclerosis (PESA) Study By Kristen N Smith, PhD, RD, LD; Mary R Dicklin, PhD; Kevin C Maki, PhD  Background: It is well accepted that a person’s lifestyle may impact…

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Use of Supplemental Long Chain Omega-3 Fatty Acids and Risk for Cardiac Death: An Updated Meta-Analysis and Review of Research Gaps

By Kevin Maki PhD | Oct 9, 2017 | 0 Comments

Use of Supplemental Long Chain Omega-3 Fatty Acids and Risk for Cardiac Death: An Updated Meta-Analysis and Review of Research Gaps By Orsolya M. Palacios, RD, PhD and Kevin C. Maki, PhD Randomized, controlled trials (RCTs) assessing the use of supplemental long chain omega-3 polyunsaturated fatty acids (LC-OM3), mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid…

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